Publications & Patents
Patents
Markowitz JE, Ulutas EZ, Pradhan A, Koveal D. Methods of measuring fluorescence and capturing movement in animals. U.S. Patent Application No. 63/678,321 (2024). Provisional patent.
Publications
Research Articles
Ulutas EZ, Pradhan A, Koveal D, Markowitz JE. High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles. bioRxiv (2024). [Preprint]
Kapri D, Pradhan A, Vuruputuri RM, Vaidya VA. Sex differences in the influence of adult‐onset hypothyroidism on hippocampal progenitor survival and neuronal differentiation in mice. J. Neuroendocrinol. (2024). DOI: 10.1111/jne.13453. [Link]
Tiwari P, Davoudian PA, Kapri D, Vuruputuri RM, Karaba LA, Sharma M, Zanni G, Balakrishnan A, Chaudhari PR, Pradhan A, Suryavanshi S, Bath KG, Ansorge MS, Fernandez-Ruiz A, Kwan AC, Vaidya VA. Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI. Neuron (2024). DOI: 10.1016/j.neuron.2024.08.016. [Link]
Singh V, Singh N, Pradhan A, Kumar Y, Bhatnagar S. Structure-activity relationships of dihydropyrimidone inhibitors against native and auto-processed human neutrophil elastase. Comput. Biol. Med. (2023). DOI: 10.1016/j.compbiomed.2023.107004. [Link]
Tiwari P, Kapri D, Pradhan A, Balakrishnan A, Chaudhari PR, Vaidya VA. Chronic hM4Di-DREADD-Mediated Chemogenetic Inhibition of Forebrain Excitatory Neurons in Postnatal or Juvenile Life Does Not Alter Adult Mood-Related Behavior. eNeuro (2022). DOI: 10.1523/ENEURO.0381-21.2021. [Link]
Saini S, Agarwal M, Pradhan A, Pareek S, Singh AK, Dhawan G, Dhawan U, Kumar Y. Exploring the role of framework mutations in enabling breadth of a cross-reactive antibody (CR3022) against the SARS-CoV-2 RBD and its variants of concern. J. Biomol. Struct. Dyn. (2022). DOI: 10.1080/07391102.2022.2030800. [Link]
Pradhan A, Saini S, Agarwal M, Kumar Y. Affinity maturation of cross-reactive CR3022 antibody against the receptor binding domain of SARS-CoV-2 via in silico site-directed mutagenesis. Research Square (2020). [Preprint]
Conferences
Poster Presentations
Pradhan A, Saini S, Agarwal M, Kumar Y. Computationally affinity matured antibody candidates against the receptor binding domain of SARS-CoV-2. 14th Vaccine Congress 2020. DOI: 10.13140/RG.2.2.34939.95527.
Pradhan A, Agarwal M, Kumar Y. Affinity Maturation of Antibodies against PD-L1 via In Silico Site-Directed Mutagenesis. Proceedings of International Conference on Drug Discovery (ICDD) 2020. DOI: 10.13140/RG.2.2.33017.01128/1. [Link]
Agarwal M, Pradhan A, Kumar Y. In-Silico Docking and Mutagenesis Studies Reveal Novel Epitopes Involved in the Interaction of Ipilimumab and Tremelimumab with Physiologically Relevant CTLA-4 Homodimer. Proceedings of International Conference on Drug Discovery (ICDD) 2020. Best Poster Award. [Link].
Pradhan A, Agarwal M, Saini S, Kumar Y. Novel Bispecific T-cell Engager (BiTE) Antibody with Enhanced anti-PD-L1 and anti-CD3 Paratopes for Onco-immunotherapy. International Conference on Emerging Areas in Biosciences and Biomedical Technologies; 2020 Feb 7-9; Indore, India.
Agarwal M, Pradhan A, Kumar Y. Coupled Bispecific Antibody: A Novel Approach for In Silico Design of Next-Generation Onco-Immunotherapeutics. International Conference on Emerging Areas in Biosciences and Biomedical Technologies; 2019 Feb 7-9; Indore, India.
Pradhan A, Joshi S, Garlapati C, Aneja R. Drug-Mediated Stress Induces Lipid Droplet Alteration in Triple-Negative Breast Cancer. Young Scientists’ Conference; 2019 Nov 5-7; India International Science Festival 2019, Kolkata, India. DOI: 10.13140/RG.2.2.34484.60809.
Pradhan A, Bajpai A, Basu S. Synthesis and Characterization of Small Molecules for Targeting Mitochondria in Cancer Treatment. 2nd International Conference on Recent Trends in Bioengineering; 2019 Feb 16; Pune, India. DOI: 10.13140/RG.2.2.26613.63207.
Science Communication
Cracking the COVID-19 Conundrum - WINStep Forward (with Manusmriti Agarwal). [Read Article]
Number of Articles Peer-Reviewed
Briefings in Bioinformatics (Oxford Academic) - 2