Publications

Publications


Research Articles


  1. Tiwari P, Kapri D, Pradhan A, Balakrishnan A, Chaudhari PR, Vaidya VA (2022). Chronic hM4Di-DREADD-Mediated Chemogenetic Inhibition of Forebrain Excitatory Neurons in Postnatal or Juvenile Life Does Not Alter Adult Mood-Related Behavior. eNeuro. DOI: 10.1523/ENEURO.0381-21.2021. [Link]

  2. Saini S, Agarwal M, Pradhan A, Pareek S, Singh AK, Dhawan G, Dhawan U, Kumar Y (2022). Exploring the role of framework mutations in enabling breadth of a cross-reactive antibody (CR3022) against the SARS-CoV-2 RBD and its variants of concern. J. Biomol. Struct. Dyn. DOI: 10.1080/07391102.2022.2030800. [Link]


Preprints


  1. Pradhan A, Saini S, Agarwal M, Kumar Y. Affinity maturation of cross-reactive CR3022 antibody against the receptor binding domain of SARS-CoV-2 via in silico site-directed mutagenesis. 2020. Research Square. [Preprint]

Conference Presentations


Poster Presentations


  • Pradhan A, Saini S, Agarwal M, Kumar Y. Computationally affinity matured antibody candidates against the receptor binding domain of SARS-CoV-2. 14th Vaccine Congress 2020. DOI: 10.13140/RG.2.2.34939.95527.

  • Pradhan A, Agarwal M, Kumar Y. Affinity Maturation of Antibodies against PD-L1 via In Silico Site-Directed Mutagenesis. Proceedings of International Conference on Drug Discovery (ICDD) 2020. DOI: 10.13140/RG.2.2.33017.01128/1. [Link]

  • Agarwal M, Pradhan A, Kumar Y. In-Silico Docking and Mutagenesis Studies Reveal Novel Epitopes Involved in the Interaction of Ipilimumab and Tremelimumab with Physiologically Relevant CTLA-4 Homodimer. Proceedings of International Conference on Drug Discovery (ICDD) 2020. Best Poster Award. [Link].

  • Pradhan A, Agarwal M, Saini S, Kumar Y. Novel Bispecific T-cell Engager (BiTE) Antibody with Enhanced anti-PD-L1 and anti-CD3 Paratopes for Onco-immunotherapy. International Conference on Emerging Areas in Biosciences and Biomedical Technologies; 2020 Feb 7-9; Indore, India.

  • Agarwal M, Pradhan A, Kumar Y. Coupled Bispecific Antibody: A Novel Approach for In Silico Design of Next-Generation Onco-Immunotherapeutics. International Conference on Emerging Areas in Biosciences and Biomedical Technologies; 2019 Feb 7-9; Indore, India.

  • Pradhan A, Joshi S, Garlapati C, Aneja R. Drug-Mediated Stress Induces Lipid Droplet Alteration in Triple-Negative Breast Cancer. Young Scientists’ Conference; 2019 Nov 5-7; India International Science Festival 2019, Kolkata, India. DOI: 10.13140/RG.2.2.34484.60809.

  • Pradhan A, Bajpai A, Basu S. Synthesis and Characterization of Small Molecules for Targeting Mitochondria in Cancer Treatment. 2nd International Conference on Recent Trends in Bioengineering; 2019 Feb 16; Pune, India. DOI: 10.13140/RG.2.2.26613.63207.

Science Communication


  • Cracking the COVID-19 Conundrum - WINStep Forward (with Manusmriti Agarwal). [Read Article]

Number of Articles Peer-Reviewed


  • Briefings in Bioinformatics (Oxford Academic) - 2